Monday, June 25, 2012

Jerry Sandusky's lawyers reveal they attempted to quit case | College football

BELLEFONTE, Pa. ? Jerry Sandusky's lawyers said Saturday they tried to quit at the start of jury selection in his child sex-abuse trial because they weren't given enough time to prepare, raising an argument on the trial's speed that might become the basis of an appeal.

Meanwhile, one of the jurors who convicted Sandusky of 45 child sex-abuse counts Friday said he was swayed by the "very convincing" testimony of eight accusers who said the former Penn State assistant coach molested them for years.

"It's hard to judge character on the stand, because you don't know these kids," juror Joshua Harper told NBC's "Today" show. "But most were very credible ? I would say all."

A day after Sandusky's conviction, his lawyers disclosed they felt too unprepared to adequately defend him because of how quickly the case was brought to trial. Experts have said the seven months between Sandusky's November arrest and trial was fast-paced by Pennsylvania standards.

"We told the trial court, the Superior Court and the Supreme Court we were not prepared to proceed to trial in June due to numerous issues, and we asked to withdraw from the case for those reasons," attorney Joe Amendola told The Associated Press.

The issues included a scheduling conflict with a defense-team member and the need to read a cache of documents produced by a lengthy grand-jury investigation. Judge John Cleland denied their request.

The attorneys raised other issues that might be part of the future appeal, saying a mistrial was sought and denied over a repetition at trial of a brief part of a November interview Sandusky had with NBC's Bob Costas.

Jurors in the two-week trial convicted Sandusky of 45 of the 48 counts against him, meaning Sandusky, 68, likely will die in prison.

Sandusky's sentencing should be in about three months; an exact date hasn't been set.

Harper said the accusers who testified one by one of horrific abuse at Sandusky's hands were each believable, "but then also the fact that we saw this corroborating story between all of them. It was very convincing."

Sandusky's impassive face when the verdict was read was confirmation for the jury, Harper said.

"I looked at him during the reading of the verdict and just the look on his face. No real emotion," he said, "because he knew it was true."

Harper said jurors had some issues with the testimony of Mike McQueary, a then-assistant who said he saw Sandusky assaulting a boy in the Penn State showers in 2001; jurors acquitted Sandusky on one count relating to the incident.

The case is poised to move to an investigation of university officials' role in reporting the charges; two former Penn State administrators ? athletic director Tim Curley and vice president Gary Schultz ? face trial on charges they didn't properly report McQueary's account of the suspected abuse in 2001.

Almost immediately after the verdict, Penn State President Rodney Erickson signaled an openness to quickly settle potential civil lawsuits arising from the convictions.

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PFT: Marshall working toward new image

89545031_display_imageGetty Images

A year after nearly making it to the playoffs following a total of six wins in three seasons, the planets aligned for another disastrous season in St. Louis.? And a disaster indeed unfolded, in the form of a 2-14 record.

The finish resulted in owner Stan Kroenke cleaning most of the house, firing G.M. Billy Devaney and coach Steve Spagnuolo.? On Saturday, Devaney joined Doug Farrar and Rob Rang of KJR radio (via NFL.com), and Devaney offered up a wide variety of excuses for the team?s re-collapse in 2011.

The laundry list of lamentations for losing include:? (1) the team went up for sale as soon as Devaney and Spagnuolo were hired; (2) the team had ?an old roster,? a ?really old roster?; (3) there were ?some guaranteed contracts on there that we have to live with?; (4) the lineup was essentially ?Steven Jackson and the Pips,? and Devaney said he ?probably would have been happier with some of the Pips? (oh . . . snap); (5) the team had to make tough and unpopular decisions regarding receiver Torry Holt and Orlando Pace; (6) there wasn?t much money being put into a team that was for sale; (7) after a successful season, offensive coordinator Pat Shurmur left to coach the Browns; (8) a ton of injuries in 2011; (9) no offseason in 2011; and (10) a ?ridiculous? schedule in 2011.

?It was just one thing after another,? Devaney said.? ?I could tell in training camp ? I mean early on, I don?t even know if we started playing a preseason game ? things just, especially on offense, things just looked really . . . nobody looked comfortable.?

Then came the regular season, with an opening slate of games against the Eagles, Giants, Ravens, Redskins, Packers, Cowboys, and Saints.? But for a postseason-altering upset win over the Saints (if New Orleans had won, the Saints would have hosted the 49ers in the divisional round), the Rams would have started the year 0-8.

?I mean, we were hoping, and this is ? we?re trying to be optimistic ? we were hoping at the halfway point, we may have had two wins,? Devaney said.? ?We thought if we could scratch out two wins, the back end of the schedule, we could win a couple of more games.? Well, I don?t know if we won any.? We may have won one, but by that time, the roster was decimated.? We were working corners out on Tuesday and they were lining up and starting for us on Sunday. . . .? Five or six of those guys, I couldn?t even tell you who they were.?

The points are all valid, but the lesson for other General Managers and coaches is that, when a team is facing that kind of adversity, it?s important to manage expectations, both inside and outside the building.

It didn?t work internally, or Devaney and Spagnuolo would have gotten another chance to preside over another stunning turnaround.

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Turkish Minister: Jet Downed in International Territory (Voice Of America)

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Sunday, June 24, 2012

Boosting blood system protein complex protects against radiation toxicity

ScienceDaily (June 24, 2012) ? New research in Nature Medicine shows that boosting a protein pathway in the body's blood making system protects mice from otherwise fatal radiation poisoning.

Scientists in the multi-institutional study -- posted online by the journal on June 24 -- say their findings open the potential for new treatments against radiation toxicity during cancer treatment or environmental exposures -- such as in a nuclear explosion or accident.

By identifying a target-specific intervention to protect the hematopoietic system against radiation toxicity, the study addresses a largely unmet challenge, according to the researchers.

"These findings suggest that pharmacologic augmentation of the activity of the Thbd-aPC pathway by recombinant Thbd (thrombomodulin) or aPC (activated protein C) might offer a rational approach to the mitigation of tissue injury and lethality caused by ionizing radiation," the scientists write in their manuscript. "Recombinant human aPC has undergone extensive clinical testing in patients, and recombinant soluble human Thbd is currently being investigated for efficacy in antithrombotic therapy in humans. Our data encourage the further evaluation of these proteins for their radio-mitigating activities."

The study reveals a previously unknown function of the Thbd-aPC pathway in radiation mitigation. The pathway is normally known for its ability to prevent the formation of blood clots and help the body fight infections. The researchers found the pathway helps blood cells in the bone marrow recover from injury caused by radiation exposure. They demonstrated that pharmacologic boosting of this pathway with two drugs tested for the treatment of thrombosis or infection (recombinant Thbd and aPC respectively) can be used in mice to prevent death caused by exposure to lethal doses of radiation.

In all instances of treatment with recombinant soluble Thbd or aPC, the result was accelerated recovery of hematopoietic progenitor cell activity in bone marrow and a reduction in the harmful effects of lethal total body irradiation. When treatment was with aPC, these benefits occurred even when treatment was delayed for 24 hours.

The scientists caution their study involves early laboratory research in mice, so it remains to be tested how the findings may translate to human treatment. Researchers also need to determine exactly why the protective function of the targeted Thbd-aPC protein pathway seems to work so well in mice.

Researchers noted that the protective benefits of Thbd-aPC occurred only in vivo in irradiated mouse models. The researchers reported that overexpressed Thbd in irradiated laboratory cell cultures did not offer the same protective benefits, as the cells did not survive. This indicates the protective benefits of Thbd on blood making cells in irradiated mouse models depends on the help of additional cells or molecules in the body, which the researchers are trying to identify in a follow-up study.

The study involves extensive multi-scientist collaborations that combined previously independent lines of research by groups at Cincinnati Children's Hospital Medical Center and the University of Ulm, Germany (led by Hartmut Geiger, PhD, Division of Experimental Hematology/Cancer Biology and the Department of Dermatology/Allergic Diseases); the University of Arkansas, Little Rock (led by Martin Hauer-Jensen, MD, PhD, Division of Radiation Health, the College of Pharmacy and the Central Arkansas Veterans Healthcare System); the Blood Research Institute in Milwaukee, Wis. (led by Hartmut Weiler, PhD); and The Scripps Research Institute in La Jolla, Calif. (led by John H. Griffin, PhD, Department of Molecular and Experimental Medicine).

The research team said the current study exemplifies a global shift to multi-investigator projects that allow a combination of varied expertise by scientists tackling complex problems from the perspective of their respective fields. This approach requires the willingness of investigators to share unpublished data and engage in an open collaboration. The researchers also said the study underscores the importance of continued federal funding for leading edge basic research that can benefit human health.

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The above story is reprinted from materials provided by Cincinnati Children's Hospital Medical Center, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Hartmut Geiger, Snehalata A Pawar, Edward J Kerschen, Kalpana J Nattamai, Irene Hernandez, Hai Po H Liang, Jose ? Fern?ndez, Jose A Cancelas, Marnie A Ryan, Olga Kustikova, Axel Schambach, Qiang Fu, Junru Wang, Louis M Fink, Karl-Uwe Petersen, Daohong Zhou, John H Griffin, Christopher Baum, Hartmut Weiler & Martin Hauer-Jensen. Pharmacological targeting of the thrombomodulin?activated protein C pathway mitigates radiation toxicity. Nature Medicine, 24 June 2012 DOI: 10.1038/nm.2813

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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NatWest opens on Sunday as IT glitch causes chaos

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Greek PM cannot attend EU summit due to surgery

FILE - Greek conservative leader Antonis Samaras takes part in a swearing in ceremony officiated by Greece's Orthodox Archbishop Ieronimos at the Presidential palace in Athens, in this Thursday, June 21, 2012 file photo. Samaras underwent surgery for a detached retina Saturday June 23, 2012. Government spokesman Simos Kedikoglou said Sunday that the doctor treating him had forbidden him from flying. So he will not be well enough to travel to a critical European Union summit in Brussels . (AP Photo/Petros Giannakouris, File)

FILE - Greek conservative leader Antonis Samaras takes part in a swearing in ceremony officiated by Greece's Orthodox Archbishop Ieronimos at the Presidential palace in Athens, in this Thursday, June 21, 2012 file photo. Samaras underwent surgery for a detached retina Saturday June 23, 2012. Government spokesman Simos Kedikoglou said Sunday that the doctor treating him had forbidden him from flying. So he will not be well enough to travel to a critical European Union summit in Brussels . (AP Photo/Petros Giannakouris, File)

(AP) ? Greece's new Prime Minister Antonis Samaras will not be well enough to travel to a critical European Union summit in Brussels after undergoing an eye operation, the government said Sunday.

Samaras, 61, underwent surgery for a detached retina Saturday, just three days after being sworn in at the head of a three-party coalition government formed after two inconclusive general elections.

The doctor treating the prime minister, Panagiotis Theodosiadis, has ruled out him being able to travel to Brussels for the June 28-29 summit, government spokesman Simos Kedikoglou said.

Samaras has appointed new Foreign Minister Dimitris Avramopoulos to head the Greek delegation at the meeting, Kedikoglou said.

Reports that the so-called troika of Greece's lenders ? the European Commission, the European Central Bank and the International Monetary Fund ? will postpone the visit of its delegation, originally planned for Monday, were not confirmed by Samaras' office.

The debt inspectors are due to review the country's fiscal situation and resume talks that had been put on hold during the country's nearly two-month political deadlock.

Greece's incoming finance minister, Vassilis Rapanos, was also hospitalized Friday after suffering a collapse. A hospital spokeswoman said he was expected to be discharged either late Monday or Tuesday after further tests. But because his swearing in had to be postponed due to his ill-health, outgoing Finance Minister Giorgos Zanias still holds the title and will attend the summit.

Zanias, who was a key negotiator for Greece's bailout deal before being named to the post, will be accompanied by Development Minister Costis Hatzidakis and Alternative Finance Minister Christos Staikouras.

Zanias himself had suffered chest pains and high blood pressure and was hospitalized last October at an EU summit, where he had accompanied then-Finance Minister Evangelos Venizelos. The doctors had said he had suffered an anxiety attack. Four days later, an adviser to then-Prime Minister George Papandreou suffered a heart attack during negotiations on Greece's second bailout deal.

The summit could prove a key test of Greek leaders' pledges to renegotiate some terms of the country's international bailout.

Greece has been dependent since May 2010 on funds from two international rescue loan deals with other European Union countries and the International Monetary Fund, in return for which it imposed a series of deep spending cuts and tax hikes.

Anti-bailout parties made massive gains in Greece's May 6 and June 17 elections, with Greeks furious at the drop in living standards by measures that have left the country struggling through a fifth year of recession and sent unemployment spiraling to above 22 percent.

Samaras' conservative New Democracy party came first in both elections, but without enough votes to govern alone. Coalition talks collapsed after 10 days in May, leading to the second ballot.

New Democracy is now in a power-sharing government with longtime socialist PASOK rivals and the small Democratic Left.

The new government on Saturday issued a policy statement outlining what it aims to change in its bailout conditions, saying it would seek to repeal some taxes, halt layoffs and extend by two years the mid-2014 deadline for tough austerity measures.

"The general aim is no more cuts to salaries and pensions, no more taxes," the statement said, adding the government would not carry out any public sector layoffs.

Whether the government can deliver on its pledges will depend on how they are viewed by Greece's international creditors. Germany, the largest single contributor to the bailout, has repeatedly said Athens must stick to its austerity targets.

____

Demetris Nellas in Athens contributed to this report.

Associated Press

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Saturday, June 23, 2012

Woolworths South Africa ropes in RedPrairie to enhance retail experience

RBR Staff Writer Published 22 June 2012

Woolworths South Africa has roped in supply chain and retail technology provider RedPrairie to provide a workforce management solution (WFM) to help improve the customer experience in-store.

RedPrairie said its WFM solution leverages engineered standards and demand-based forecasts to optimize scheduling, task assignment, and performance measurement as well as compute and pay incentives.

Woolworths plans to use RedPrairie's WFM to leverage point of sale data to generate accurate forecasting and to improve compliance with optimised schedules.

The global supply chain firm claims that its solution will give managers visibility of key performance indicators and tools to manage performance, ensuring that the right persons are available in the right place at the right time.

RedPrairie senior vice president Andrew Kirkwood said, "The performance management capabilities of our workforce solution will enable Woolworths to better serve its customers by more efficiently managing its workforce."

Woolworths, which operates more than 400 retail stores in the country, offers customers a wide range of clothing, food, homeware and beauty products as well as financial services.

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